A drug used, amongst other indications, to reduce the formation of cerebrospinal fluidThis clear, water-like fluid forms, for the most part, within the brain, more specifically inside the ventricles of the brain. Blood flows through structures inside the ventricles, called the choroid plexuses, and clear fluid is produced as a result, passing into the ventricle. This process is akin to blood flowing through the kidneys and urine being produced as a result. An important difference is that, unlike urine, the cerebrospinal fluid is not passed out of the body periodically. Instead, the fluid is re-absorbed back into the blood stream, mostly via the arachnoid granulations, into the cerebral venous sinuses. In the course of a 24-hour period, most healthy adults will produce about 500mls (or a pint) of cerebrospinal fluid, although at.... In a minority of people it can relieve headaches associated with Chiari malformations. See also Furosemide (Frusemide)A drug belonging to a class known as diuretics, meaning that they cause the person taking them to pass more urine than usual. Diuretics are used in the treatment of heart failure or high blood pressure. They also reduce the rate at which cerebrospinal fluid is formed by the choroid plexus and can sometimes relieve symptoms of Chiari malformation by reducing the “pressure from above”, which may tend to push the herniated cerebellar tonsils into the foramen magnum. Another drug which has similar effects is acetazolamide but many people do not tolerate some of the side effects of this preparation..