Drugs, belonging to a number of different classes, which modify the transmission of electrical impulses in the brain and spinal cordThe main nerve trunk running down the spinal canal and connecting the individual’s mind and consciousness to the rest of his or her body. It is about the size of a person’s little finger, in diameter. It cannot repair itself if damaged.. Most often they are prescribed to treat neuropathic painMost of the pains that we experience result from normal nerve endings being stimulated by injury, or inflammation, or by stretching of or pressure put upon the affected parts. When, however, the nerves or the sensory tracts in the spinal cord become damaged or disrupted by disease, then normal sensory signals become distorted and perceived as pain. Alternatively, pain pathways themselves generate pain signals in the absence of any peripheral stimulus.. The most common classes of drugs used in this way are antiepileptic drugs and antidepressants. Developed originally to treat, respectively, epilepsy and profound mood disorders, these drugs, by modifying the complex chemistry of the brain and spinal cordThe main nerve trunk running down the spinal canal and connecting the individual’s mind and consciousness to the rest of his or her body. It is about the size of a person’s little finger, in diameter. It cannot repair itself if damaged., can, as beneficial side effects, also reduce the conduction of pain impulses.